Details for gene set NCI_SPHINGOSINE 1-PHOSPHATE (S1P) PATHWAY[GSEA]

Table: GSEA Results Summary

Dataset	Set_04_transDMpreB_versus_WTpreB.phenotype_transDMpreB_versus_WTpreB.cls #transDMpreB_versus_WTpreB
Phenotype	phenotype_transDMpreB_versus_WTpreB.cls#transDMpreB_versus_WTpreB
Upregulated in class	WTpreB
GeneSet	NCI_SPHINGOSINE 1-PHOSPHATE (S1P) PATHWAY
Enrichment Score (ES)	-0.6716831
Normalized Enrichment Score (NES)	-1.6839583
Nominal p-value	0.0
FDR q-value	0.032019023
FWER p-Value	0.132

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	CYCS	8821	708	3.673	-0.0141	No
2	BAX	17832	898	3.158	-0.0035	No
3	CTSD	22	1426	2.192	-0.0175	No
4	GRB7	20673	1581	1.934	-0.0131	No
5	VEGFA	22969	1761	1.685	-0.0116	No
6	MAPK8	6459	2014	1.381	-0.0162	No
7	PRKCZ	5260	2053	1.330	-0.0094	No
8	BID	17017 435	2337	1.007	-0.0181	No
9	ASAH1	3835 3853 8630	2346	1.004	-0.0119	No
10	MAP2K1	19082	2547	0.862	-0.0170	No
11	GNA15	19671	2672	0.770	-0.0187	No
12	ITGB3	20631	2859	0.619	-0.0246	No
13	EGF	15169	3071	0.478	-0.0329	No
14	SNX15	23993 3761	3104	0.460	-0.0316	No
15	MAP2K2	19933	3294	0.375	-0.0393	No
16	BCL2	8651 3928 13864 4435 981 4062 13863 4027	3317	0.365	-0.0381	No
17	SLC9A3R2	23089 1544 1514	3401	0.330	-0.0404	No
18	BAG4	7431	3485	0.304	-0.0429	No
19	GNAQ	4786 23909 3685	3763	0.235	-0.0563	No
20	AKT1	8568	4184	0.164	-0.0780	No
21	FOS	21202	4219	0.162	-0.0787	No
22	BCAR1	18741	4251	0.158	-0.0794	No
23	PLCB2	5262	4288	0.153	-0.0803	No
24	ABL1	2693 4301 2794	4314	0.151	-0.0807	No
25	PAK1	9527	4333	0.148	-0.0807	No
26	SHC1	9813 9812 5430	4421	0.139	-0.0844	No
27	STAT5A	20664	4510	0.131	-0.0883	No
28	PDGFRB	23539	4579	0.125	-0.0912	No
29	SHB	10493	4664	0.118	-0.0949	No
30	HRAS	4868	4707	0.115	-0.0965	No
31	PTPN1	5325	5029	0.095	-0.1132	No
32	FADD	17536 8950 4711	5614	0.068	-0.1443	No
33	PTPN2	23414	5764	0.062	-0.1520	No
34	NCK1	9447 5152	5996	0.056	-0.1641	No
35	ACP1	4317	6039	0.055	-0.1660	No
36	SRC	5507	6271	0.049	-0.1782	No
37	CRADD	19640	6331	0.047	-0.1810	No
38	RHOA	8624 4409 4410	6494	0.044	-0.1895	No
39	GRB10	4799	6977	0.035	-0.2153	No
40	HIF1A	4850	7022	0.034	-0.2175	No
41	CDC42	4503 8722 4504 2465	7363	0.028	-0.2357	No
42	PDGFB	22199 2311	8287	0.016	-0.2855	No
43	GNA14	23907	8561	0.012	-0.3001	No
44	SMPD3	18757	8887	0.008	-0.3177	No
45	IGF1	3352 9156 3409	8900	0.008	-0.3183	No
46	GNAO1	4785 3829	9360	0.002	-0.3431	No
47	GNAI1	9024	9570	-0.001	-0.3543	No
48	PAWR	19885 658	9735	-0.003	-0.3632	No
49	LYN	16281	9750	-0.003	-0.3639	No
50	PLCG1	14753	9775	-0.004	-0.3652	No
51	STAT5B	20222	10037	-0.007	-0.3793	No
52	KDR	16509	10530	-0.013	-0.4058	No
53	DOK1	17104 1018 1177	10626	-0.015	-0.4108	No
54	SOS1	5476	10751	-0.016	-0.4174	No
55	PTGS2	5317 9655	10832	-0.017	-0.4216	No
56	SPHK2	1217 1806 12155	11209	-0.023	-0.4418	No
57	IRS1	4925	11570	-0.028	-0.4611	No
58	PIK3R1	3170	11694	-0.031	-0.4675	No
59	GNAI3	15198	11722	-0.031	-0.4688	No
60	TRAF2	14657	11751	-0.032	-0.4701	No
61	CBL	19154	11843	-0.033	-0.4748	No
62	PTPN11	5326 16391 9660	12087	-0.038	-0.4877	No
63	YES1	5930	12441	-0.046	-0.5064	No
64	GNA12	9023	12591	-0.050	-0.5142	No
65	TNF	23004	12665	-0.052	-0.5178	No
66	FLT1	3483 16287	13007	-0.061	-0.5358	No
67	PDGFA	5237	13612	-0.087	-0.5679	No
68	PIK3CA	9562	13936	-0.107	-0.5846	No
69	VAV2	5848 2670	14239	-0.130	-0.6001	No
70	SPHK1	5484 1266 1402	14328	-0.138	-0.6040	No
71	JAK2	23893 9197 3706	14343	-0.140	-0.6038	No
72	GNAZ	71	14892	-0.214	-0.6320	No
73	MYC	22465 9435	14983	-0.233	-0.6353	No
74	FYN	3375 3395 20052	15076	-0.254	-0.6386	No
75	AIFM1	2558 24161	15127	-0.263	-0.6396	No
76	TNFRSF1A	1181 10206	15257	-0.296	-0.6446	No
77	LRP1	9284	15456	-0.363	-0.6529	No
78	FGR	4723	15626	-0.432	-0.6592	No
79	MAP4K4	11241	15629	-0.433	-0.6565	No
80	CDH5	18512	15869	-0.553	-0.6658	No
81	RIPK1	5381	15903	-0.580	-0.6637	No
82	HCK	14787	15955	-0.616	-0.6624	No
83	ITGAV	4931	15957	-0.618	-0.6584	No
84	PTPRJ	9664	16204	-0.867	-0.6660	Yes
85	RASA1	10174	16303	-0.967	-0.6649	Yes
86	MAPK14	23313	16395	-1.021	-0.6631	Yes
87	BIRC3	19247	16436	-1.055	-0.6583	Yes
88	PRKCD	21897	16559	-1.188	-0.6570	Yes
89	RAF1	17035	16625	-1.259	-0.6523	Yes
90	MAPK3	6458 11170	16645	-1.295	-0.6447	Yes
91	CASP8	8694	16729	-1.404	-0.6400	Yes
92	GNA11	3300 3345 19670	16744	-1.435	-0.6313	Yes
93	NCK2	9448	16752	-1.454	-0.6221	Yes
94	RAC1	16302	16919	-1.693	-0.6199	Yes
95	SMPD1	18145 2658	17033	-1.831	-0.6139	Yes
96	GRB2	20149	17099	-1.953	-0.6046	Yes
97	SGPL1	19757	17188	-2.123	-0.5953	Yes
98	SGPP1	21039	17309	-2.313	-0.5866	Yes
99	SLC9A3R1	11250	17339	-2.365	-0.5725	Yes
100	AKT3	13739 982	17441	-2.539	-0.5613	Yes
101	MAP2K4	20405	17452	-2.546	-0.5450	Yes
102	GNA13	20617	17564	-2.763	-0.5328	Yes
103	BAD	24000	17607	-2.854	-0.5163	Yes
104	NFKBIA	21065	17794	-3.356	-0.5042	Yes
105	RELA	23783	17808	-3.389	-0.4826	Yes
106	DNM2	4635 3103	17822	-3.423	-0.4607	Yes
107	PRKRA	357	17904	-3.689	-0.4407	Yes
108	NFKB1	15160	17907	-3.696	-0.4165	Yes
109	JUN	15832	17929	-3.751	-0.3929	Yes
110	MAP3K1	21348	18225	-4.997	-0.3759	Yes
111	PTEN	5305	18232	-5.045	-0.3430	Yes
112	CSK	8805	18265	-5.201	-0.3104	Yes
113	GAB1	18828	18330	-5.503	-0.2776	Yes
114	STAT1	3936 5524	18359	-5.675	-0.2417	Yes
115	STAT3	5525 9906	18377	-5.818	-0.2043	Yes
116	LCK	15746	18405	-6.029	-0.1660	Yes
117	CXCR4	13844	18566	-8.219	-0.1204	Yes
118	MAPK1	1642 11167	18603	-9.259	-0.0613	Yes
119	BLK	3205 21791	18607	-9.402	0.0005	Yes